YANG Qian.Mucosal vaccination in pigs: prospects and challenges[J].Journal of Nanjing Agricultural University,2018,41(2):218-222.[doi:10.7685/jnau.201712003]





Mucosal vaccination in pigs: prospects and challenges
南京农业大学动物医学院, 江苏 南京 210095
College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China
mucosal vaccinationpignasal vaccinationoral vaccinationadvance
The respiratory tract or gastrointestinal tract is one of the main entry sites for most pathogens. Mucosal delivery of vaccines could cut off the entering route of pathogens if the local immunity is established. The mucosal vaccination has gained more and more attention since majority of swine infectious diseases are caused by mucosa invasion. Firstly the advantages and challenges of oral vaccination and nasal vaccination were put forward. Then the advances of vaccination designs were described for the challenges. The efficiency of oral immunization could be improved by mucosal immunostimulants and antigen delivery system. Both nasal immunization and oral immunization are the routes to prevent infectious diseases in pigs. In summary the review provided an effective strategy to design mucosal vaccines in pig.


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更新日期/Last Update: 1900-01-01